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Accelerating escalation is generally not recommended, as the gradual protocol serves important pharmacodynamic purposes beyond simple tolerability

Identification of the putrescine biosynthetic genes in Pseudomonas aeruginosa and characterization of agmatine deiminase and N-carbamoylputrescine amidohydrolase of the arginine decarboxylase pathway

De Souza RL, Matsuura M, Eckstein F, Rawlinson SC, Lanyon LE, Pitsillides AA

Lyophilized (freeze-dried) peptide should be stored at minus 20 degrees Celsius (minus 4 degrees Fahrenheit) for long-term storage

10.1073/pnas.76.1.56 429 MurogaY.TagawaH.HiragiY.UekiT.KataokaM.IzumiY.et al (1988)

Such values allow to measure drug absorption, distribution, metabolism and excretion rates, and form a critical starting point for the development and optimization of dosing regimens