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Amphetamine enters presynaptic neurons by passive diffusion and through plasma membrane monoamine transporters, including the dopamine transporter (DAT) in dopaminergic neurons, the norepinephrine transporter (NET) in adrenergic neurons, and the serotonin transporter (SERT) in serotinergic neurons

They may be prescribed for people with obesity

Researchers using these peptides should understand they are working with promising but preliminary evidence, not settled science

Curcumin may help lower inflammatory signaling, with modest benefits in joint pain

In clinical trials, the increased insulin sensitivity improved weight loss, ovulation, menstrual regularity, and even androgen levels, all important for managing PCOS symptoms

Hypothesis-generating approaches Hypothesis-generating interventions rely on mechanistic reasoning or preliminary preclinical/clinical data, requiring further validation in humans