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To study the role of GLP-1R in microglial inflammation, BV-2 cells were preincubated with the selective GLP-1R agonist liraglutide (100 nM, Selleck, TX, USA) and the antagonist exendin(939) (200 nM, MCE, USA) for 24 h, followed by LPS (1 g/ml, SigmaAldrich, MO, USA) stimulation for 24 h
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Oral formulations represent a major shift in accessibility and convenience, but they come with different pharmacokinetic profiles that affect onset and timeline
Prevalence of childhood and adult obesity in the United States, 2011-2012
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