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Researchers propose the relief lies not in weight reduction, but in GLP1s ability to decrease intracranial pressure

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While circulating levels of PYY 3-36 are frequently reduced in individuals with obesity 31,32,33,34,35 , these levels typically return to those detected in average-weight individuals following a reduction in body weight and/or gastric bypass surgery 32,33,35

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The same study also demonstrated that the decrease in blood pressure, cholesterol and HbA1c levels associated with semaglutide reverted to baseline following drug withdrawal