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In chronic mild stress models, the attenuation of serum corticotropin-releasing factor and cortisol levels by tribulus saponins suggest normalization of hypothalamic-pituitary-adrenal (HPA) axis hyperactivity (31)

Cerebrospinal fluid metabolomic and proteomic characterization of neurologic post-acute sequelae of SARS-CoV-2 infection

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Best for: Research protocols requiring larger doses, as it keeps the injection volume small

The other risk is chemical contamination, either from certain types of plastic containers, or from chemical vapors that pass through the walls of the water containers