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Low circulating IGF-I bioactivity is associated with human longevity: findings in centenarians offspring

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Ind Crop Prod 49:697704 [Google Scholar] Vacca A, Nativi C, Cacciarini M, Pergoli R, Roelens S (2004) A new tripodal receptor for molecular recognition of monosaccharides

Statistical significance was assessed using a two-tailed paired t-test

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The Hallmarks of Aging: Why Longevity Matters In 2013, scientists identified nine biological hallmarks of aging, including: Genomic instability Telomere attrition Mitochondrial dysfunction Chronic inflammation (or inflammaging) Each hallmark contributes to the functional decline associated with aging