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As a consequence, the main mitochondrial proteome (~1500 proteins) is encoded by the nucleus, translated in the cytosol and imported into the mitochondria through specific translocator complexes (TIM and TOM) of the inner mitochondrial membrane (IMM) and outer mitochondrial membrane (OMM), respectively

doi: 10.1016/j.metabol.2006.08.015 120 FascioloGNapolitanoGAprileMCataldiSCostaVCiccodicolaAet al

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These estimates assume consistent medication use, regular physical activity, and mindful eating habits

& Stefnsson, E