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(1997): Progressive decrease of cerebral cytochrome C oxidase activity in sparse-fur mice: role of acetyl-L-carnitine in restoring the ammonia-induced cerebral energy depletion

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After demonstrating its effect in animal studies, such as its effect to improve glucose tolerance after gastric glucose administration in mice (51), a 4 week clinical study was undertaken in drug-nave patients with type 2 diabetes (52)

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