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Conversely, TMAO dose-dependently augmented ERK1/2 pathway activation and myofibroblast trans-differentiation, when co-administered with TGF-1 in comparison to TGF-1 or TMAO alone, without affecting SMAD3 phosphorylation (Fig

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Mima A, Gotoda H, Lee R, Murakami A, Akai R, Lee S

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Increase your protein and fiber intake to help manage hunger