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Results were interpreted based on the cut-off values given by the manufacturer

This shift triggers mitochondrial outer membrane permeabilization (MOMP), resulting in cytochrome c release and the initiation of caspase-dependent apoptosis [215, 216]

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Because TrxR1 plays a vital role in resolving oxidative damage on Trx and other target proteins, TrxR1 and the activity of the Trx system is most important to the cell under conditions of oxidative stress or chemotherapeutic assault

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