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This pigment is also seen in combination with liver fibrosis and cirrhosis, bile duct proliferation, periportal inflammation, and hepatocarcinogenesis (Kanel and Korula 2005

There is no way to reverse oxidative damage once it occurs

NSAID-Induced Gut Damage Long-term NSAID use can erode the stomach lining and small intestine, leading to pain, bleeding, and poor nutrient absorption

Por ello, en la actualidad se cuenta con 7 presentaciones farmacolgicas para su uso en el tratamiento de la DM2 como frmaco de segunda lnea o de primera lnea cuando la metformina est contra-indicada

doi:10.3390/ijms16047210 76

Cloudy vial after reconstitution: do not use