In another study, NAC supplementation had no significant effect on serum levels of sex hormone-binding globulin (SHBG), LH, FSH, LH/FSH, E2 and testosterone in PCOS patients after 12 weeks (Reference Ghomian, Khadem and Moeindarbari5,Reference Nasr9,Reference Nemati, Nemati and Taheri12,Reference Badawy, State and Abdelgawad13)
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Biochimica et Biophysica Acta (BBA) - General Subjects, 1790 (10), 11491160
Data extraction focused on the study design, population characteristics, IF protocols, and reported outcomes
Transcriptional activation of the GSTP1 gene is also regulated by the Nrf2 pathway (165)
Data on hypothyroidism and OS, both in humans and dogs, are particularly conflicting