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In experimental systems, receptor activation by Cagrilintide has been associated with modulation of neuronal signaling pathways within hindbrain regions involved in metabolic regulation [1]

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As low levels of GH/IGF were also reported to delay puberty and reproduction in KO models, it seems feasible that this axis may be working by shifting a biological timer and delaying aging as a consequence, which may defer as well the arrival of age-related diseases (253)

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Carcinogenesis 1998