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The copper chelator tetrathiomolybdate, which blocks the copper-dependent catalytic activity of LOX, is presently undergoing a phase II study (NCT00195091) involving patients with breast cancer at moderate to high risk of recurrence

That color shift is a discard signal even if the calendar says the vial is still in window

Contact your provider if you experience intractable vomiting (unable to keep down fluids for more than 24 hours), severe abdominal pain (particularly if constant or radiating to the back), or signs of dehydration including decreased urination, extreme thirst, dizziness, or confusion

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