TB-500 is also banned by WADA and most professional sports leagues
10.4103/0973-7847.70902 165 LopezS
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It depends on your dose, how consistent you are, your health, how much sun you get, your genetics, and how severe your pigmentation is
References (this section): NEJM (2023): Phase 2 trial publication Eli Lilly: Phase 2 results (mentions 24.2% at 48 weeks as a secondary endpoint) Eli Lilly (Dec 2025): Phase 3 TRIUMPH-4 topline results announcement Retatrutide side effects: what trials report (not medical advice) Searches like retatrutide side effects and side effects of retatrutide usually refer to events reported in clinical trial publications and sponsor summaries
The science underlying peptides, useful guidelines for safe injection technique, and how to include them into an aesthetic practice is discussed in this paper