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Oea signaling pathways and the metabolic benefits of vertical sleeve gastrectomy

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TNF- enhances inflammation via the pro-survival transcription factor NF-B, and GLP-1RAs have been shown to inhibit NF-B activation[6]

Data from the Look Action for Health in Diabetes (AHEAD) Trial showed that an intensive lifestyle intervention aimed at weight loss reduced the incidence of obesity-related cancers by 16% in adults with overweight or obesity and T2D after a median follow-up of 11 years [45]

Obesity and cancer risk: Emerging biological mechanisms and perspectives