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We therefore suggest a mechanism that can be described according to the Cleland nomenclature as a combination of a random bi-uni mechanism and a ping-pong bi-bi (or uni-uni-uni-uni) mechanism in which the single product of the rate-limiting random mechanism becomes the first substrate of the ping-pong mechanism (Fig

The research framing discusses defined multi-week blocks commonly in the range of roughly 812 weeks followed by an off period before repeating, with the aim of limiting receptor down-regulation

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This may be why there arent currently any studies that have explored this method of delivery

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