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Thus, all three of the main UA transporters may contribute to the brain concentrations of UA through their action at the blood-brain barrier, although ABCG2 is thought to have the greatest effect, probably acting to remove UA from brain to blood 45

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Co-administration of iRGD with sorafenib-loaded iron-based metal-organic framework as a targeted ferroptosis agent for liver cancer therapy

Wang ES, Frankfurt O, Orford KW, Bennett M, Konopleva M