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10.16306/j.1008-861x.2021.06.002 18 GongX

Together, these intriguing findings demonstrate that RSL3 can effectively induce DNA damage, impair DNA damage repair response, and trigger autophagy in thyroid cancer cells by inhibiting GPX4

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However, this limitation does not fully prevent its clinical utility as a glutathione precursor: once deacetylated cysteine reaches target cells, intracellular synthesis proceeds effectively

This broad gene-level effect suggests GHK-Cu may influence healing at a more fundamental level than peptides with narrower mechanisms