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People with a personal or family history of medullary thyroid cancer or multiple endocrine neoplasia syndrome type 2 (MEN 2) should not use Retatrutide

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These include homomeric GluK1 bound to agonist Glu (Selvakumar et al., 2021), homomeric GluK2 bound to the positive allosteric modulator (PAM) BPAM344 (BPAM) (Kumari et al., 2020)

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