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The peptides influence on over 4,000 human genes means its effects extend well beyond the dermis
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If you want the complete chemistry, read our full chemistry deep dive explaining exactly why NAD+ is a coenzyme and not a peptide, with the molecular difference broken down in clear, everyday language
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The compound is very interesting from a medical point of view, as it has effect to almost all organs in extremely low concentrations (in a range from ng to mg and more per a kilogram of body weight) and without any toxic or side effects