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PLoS One 11(11):e0165595 Yu Q, Stamenkovic I (2000) Cell surface-localized matrix metalloproteinase-9 proteolytically activates TGF-beta and promotes tumor invasion and angiogenesis

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Symptoms of vitamin C deficiency The signs of a Vitamin C deficiency can vary from person to person, but they may include one or more of the following: Rough, dry, damaged, bumpy skin Unexplained weight gain Easy bruising Fatigue, poor mood Bright red hair follicles Chronic stress and inflammation Fingernails spoon shaped with red lines or spots Pain swelling in joints Tooth loss and bleeding gums Slow wound healing Poor immune system Persistent iron deficiency anemia The most common risk factors for vitamin C deficiency are unhealthy diet, anorexia, alcoholism, smoking, severe mental illness, and dialysis

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Hair loss, mood, and other concerns Search interest around cagrilintide side effects often includes hair loss and depression