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Performing urinalysis, cytologic analysis, ascites cytochemistry, chest x-ray, and cultures are recommended for the timely identification of infectious processes

Significance was estimated with one-tail Fishers exact tests corrected using the Benjamini-Hochberg approach

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In STEP-1 (Wilding et al., NEJM 2021), 68 weeks of once-weekly 2.4 mg semaglutide plus lifestyle intervention produced a mean body-weight reduction of about 15%, versus about 2.4% with placebo a large, clinically meaningful, well-replicated effect

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