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The above evidence converges to support the hypothesis that metabolic dysregulation, characterized by impaired glycolysis and PDH dysfunction, underlies the mitochondrial dysfunction observed in ME/CFS
The study findings were published in the journal JAMA Internal Medicine on March 28, 2022
Grabinska, Jean Kanyo, Adam Liu, Tukiet Lam, View ORCID ProfileHongying Shen doi: Summary Organelle transporters define metabolic compartmentalization and how this metabolite transport process can be modulated is poorly explored
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