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GLP-1 receptor agonists like semaglutide are designed to mimic this effect, which is a primary reason they are effective for weight loss
GLP-1 agonists, such as semaglutide or tirzepatide, act on the GLP-1 receptor to suppress appetite and to regulate glycemia
The PlexusDx Precision Peptide Genetic Test analyzes variants in four critical pathways: the GIPR rs1800437 variant affects your GIP receptor sensitivity, GLP1R rs6923761 influences GLP-1 pathway responsiveness, FTO rs9939609 shapes your metabolic predisposition to weight gain, and MC4R rs17782313 impacts your appetite regulation pathways
If those monotherapies falter, or you just want to start out by throwing the kitchen sink at the problem, BlueChew may be the better resource