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Supplements and Over-the-Counter Products to Avoid High-dose vitamin and mineral supplements taken near your semaglutide dose can bind in your digestive tract and reduce absorption of both substances

Nakhal et al., 2025b)

Supplementation was shown to improve insulin resistance and oxidative stress, along with clinical manifestations like hirsutism in PCOS subjects ( Figure 5 )

These effects are therapeutic and contribute to the medication's efficacy in achieving weight loss

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Moreover, 75% of participants in the treated groups reported decreased shedding, and 67% perceived their hair as healthier by the end of the study