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uremia (R), and ketoacidosis (K) [12]

The multifaceted actions of VIP make it a promising target for therapeutic applications in various conditions, such as gastrointestinal disorders, inflammatory diseases, and neurological conditions

The result is accelerated revascularization that can transform the healing environment within days of starting treatment

Melatonin is a well-studied sleep-timing hormone

Harris et al., 2023) - although other agents such as Salicylic Acid Analogues (Song et al., 2016) and Mannitol have been demonstrated in intra-arterial administration in rodent ischemic stroke models (Song et al., 2016