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JCI Insight 4 , 124203 (2019)

Exercise & Athletic Performance Lysine supplements may play an important role in building and maintaining muscle tissue, making it popular among athletes (x)

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A 2019 review in the Journal of Physiology noted that "IGF-1 signalling and mechanical loading converge on mTORC1 to regulate skeletal muscle protein synthesis, and the relative contribution of each remains an active area of investigation" [6]