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The least-squares mean percentage change in body weight from baseline was -7.2% in the 1 mg group, -12.9% in the 4 mg group (starting at 2 mg), -17.1% in the combined 4 mg groups, -17.5% in the combined 8 mg groups, and -17.5% in the 12 mg group, compared with -1.6% in the placebo group

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Taheri S, Lin L, Austin D, Young T, Mignot E

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J Clin Invest 124: 4473-4488, 2014

Considerations for Older Adults and Multiple Health Conditions Older adults with CKD often face multiple health challenges, making them more prone to drug interactions and side effects when starting GLP-1 therapy