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Phenytoin is a potent inducer of CYP 2C9, 2C19, and 3A4, resulting in innumerable drug-drug interactions.(34300194) interactions between phenytoin and valproate Effect on phenytoin: Valproate inhibits CYP2C9, resulting in the accumulation of phenytoin

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D'Ambrosio et al engineered by a frame-shift mutation a human IGF-1R cDNA that produces 486 amino acids long receptor

The difference between a result and a risk is rarely the peptide itself