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38 Thus, these findings support the concept that circulating TGF 1 promotes the BBB permeability observed in vivo primarily through the downregulation of claudin-5

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This reaction is catalyzed by the enzyme fatty acyl-CoA synthetase and driven to completion by inorganic pyrophosphatase

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TKIs interfere with cellular signaling pathways, which may contribute to inner ear toxicity (Rizk et al