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If left untreated, vitamin B12 deficiency can lead to severe problems, including neurological (nervous system) damage that cant be reversed

One study found that hydroxychloroquine, which was prescribed for rheumatoid arthritis and lupus, did not cause hemolysis in 11 African American patients with G6PD deficiency.[ref] With Primaquine, which is dosed on a weekly schedule, there is a need for medical supervision and pre-treatment screening for G6PD.[ref][ref] Quinine has been used for centuries to combat malaria

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Folinic acid produced significant improvements in global ADOS score, social interaction, and communication, whereas placebo showed no meaningful change (Renard et al., 2020)

some protocols repeat more frequently depending on study design

In order to avoid dangerous interactions, be sure to let your prescriber know what medications you are taking