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When stressed, neurones limit their activity to preserve energy

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GAL binds all three receptor subtypes (GALR1, GALR2, and GALR3) with similar affinities whereas, GALP binds with highest affinity to GALR3 followed by GALR2 with GALR1 binding with least affinity

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an acidic TFA solution is to be used to remove Mmt and Mtt protecting groups 6-12 times, which increases the complexity of the operation