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In this respect, it is noteworthy that vascular endothelium is known to play a critical role in regulation of inflammatory processes [9] and that cell adhesion molecules such as vascular cell adhesion molecule-1 (VCAM1), as well as proinflammatory cytokines, play key roles in the pathogenesis of EM [10]
Affinity purified protein samples were further resolved by size exclusion chromatography and assessed by SDS-PAGE and negative stain TEM before vitrification and cryo-EM imaging (Supplementary Fig
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