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So far, berberine can be administered only via the oral route
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However, similar to other chronic diseases such as T2D, the focus in obesity management (including pharmacotherapy prescription) over time will need to be shifted to primary care and collaborative integrated care models to be developed between specialist obesity services and primary care striving to meet the needs of people living with obesity [115]
The parenteral route remains dominant in the market due to the bioavailability challenges of peptide-based therapies
Recent data reported by the International Diabetes Federation (IDF) in 2021 have demonstrated that the global prevalence of diabetes was estimated at 10.5% (approximately 537 million people) (Sun H
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