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In DM, hyperglycemia-induced ROS production worsens beta-cell failure and insulin resistance through pathways such as the AGE-RAGE signaling, protein kinase C (PKC) activation, and the polyol pathway

It is one of the most extensively studied pentadecapeptides in published research literature, frequently referenced in tissue repair, gastrointestinal signalling, and angiogenesis research models

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However, the mechanism by which truncated Syn variants sequester cellular proteins and damaged organelles to drive LB nucleation remains poorly understood

Catalase enhances viability of human chondrocytes in culture by reducing reactive oxygen species and counteracting tumor necrosis factor--induced apoptosis

S., Kodanaz, A