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Food and Drug Administration states that it does not have enough safety information to determine whether compounded BPC-157 may harm humans

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Most people tolerate B12 supplementation well, even at doses significantly higher than the recommended daily amount

It is also advised to avoid mega doses of pyridoxine in pregnant or breastfeeding patients unless necessary, since safety data for doses beyond the recommended dietary allowance are limited

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Men and women 60 years or older have average dietary intakes of 5.6 g/day and 3.7 g/day, respectively (126)