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Elderly, Cachectic, or Debilitated Patients: Life-threatening respiratory depression is more likely to occur in elderly, cachectic, or debilitated patients because they may have altered pharmacokinetics or altered clearance compared to younger, healthier patients (see WARNINGS, Life-Threatening Respiratory Depression)
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3MST and R196G also decreased the GSH level in the presence of 3MP, while C247S and R187G did not (Fig
doi: 10.3390/PHARMACEUTICS15102406 101 KontoghiorghesGJKontoghiorgheCN
However, because the FDA has not approved this treatment for skin whitening , it is crucial to consider potential side effects before choosing it