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We further demonstrate that a senolytic FOXO4-D-retro-inverso-isoform peptide (FOXO4-DRI) promotes apoptosis and decreases G0/G1 phase cells in pro-senescence models of keloid organ cultures and fibroblasts, accompanied with p53-pS15 nuclear exclusion

Gene Ther 12:891901 Garaci E, Palamara AT, di Francesco P, Favalli C, Ciriolo MR, Rotilio G (1992) Glutathione inhibits replication and expression of viral proteins in cultured cells infected with Sendai virus

High activity of NNMT is also correlated with lower levels of glucose transporter 4 (GLUT4), which is vital for glucose uptake from the bloodstream into fat and muscle cells

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Gartner A, Boag PR, Blackwell TK (2018) Germline Survival and Apoptosis