As ATP production becomes more efficient and less toxic, patients often report a gradual lifting of the heavy, leaden feeling in their limbs, a reduction in the severity of post-exertional crashes, and an improvement in their overall stamina and cognitive clarity
Distinguishing GLP-1 Side Effects from Other Musculoskeletal Causes Body aches occurring during GLP-1 treatment may stem from medication effects, rapid weight loss altering joint biomechanics, dehydration, electrolyte imbalances, increased physical activity with new energy levels, or pre-existing conditions unrelated to medication
But the absolute amount of lean mass lost is still significant because the total weight loss is so large
Arslanian S, Gies I, Goldman B, Karlsson T, Kelly AS, Skalshi Kjr M, et al
If your total energy intake is low, your body prioritises using that energy for brain and vital organ functions, like your heart pumping blood around your body and your kidneys filtering waste and forming urine, as opposed to maintaining or building muscle
Spread intake throughout the day rather than drinking large volumes at once, which can trigger nausea when your GLP-1 dose is active and gastric emptying is slowed