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Regional Analysis North America led the GLP-1 market with a 57% share in 2025, due to the high prevalence of obesity and type 2 diabetes, alongside a healthcare system where there is early access to new medications via the FDAs fast-track pathway and extensive insurance that makes such expensive medications accessible to millions of patients

Among 13 identified lipid metabolites, 11-Dehydro thromboxane B2, 2-Methoxyestrone, 7-Hydroxytestosterone, Ergosterol, geranyl pp, and PC 36:1 were involved in pathways such as Arachidonic acid metabolism, Serotonergic synapse, Steroid hormone biosynthesis, Glycerophospholipid metabolism, Linoleic acid and -Linolenic acid metabolism (Figure 6E)