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Use with Caution: History of pancreatitis (safety not established in patients with prior pancreatitis) Severe gastrointestinal disease Diabetic retinopathy complications

Effects of GLP-1RAs on angiogenesis, CBF, and infarct volume In mice with focal cerebral cortical ischemia induced by MCAO, intraperitoneal administration of once-daily liraglutide (for 14 days), 24 h following stroke induction, promoted angiogenesis through significantly increasing the expression of vascular endothelial growth factor (VEGF) in cerebral ischemic areas as compared to normal saline treatment [65]

Dazzi C, Cariello A, Giovanis P, Monti M, Vertogen B, Leoni M, et al

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Here's what we'll cover Here's what we'll cover Here's what we'll cover Key takeaways Theres no clear link between semaglutide and anxiety but some people have reported feeling anxious or panicky after starting it