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For anti-aging purposes, a lower dose is often sufficient, while higher doses may be required for wound healing or immune support

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Understanding how leucine affects energy generation could lead to therapies for metabolic disorders, fatigue syndromes, and age-related diseases involving reduced mitochondrial efficiency

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J Cell Biol 138:13791394 Chen C, Krausz KW, Idle JR, Gonzalez FJ (2008) Identification of novel toxicity-associated metabolites by metabolomics and mass isotopomer analysis of acetaminophen metabolism in wild-type and Cyp2e1-null mice

95,96,97 The expression of ZIP8 mRNA is upregulated by cadmium in an NF-B-dependent manner, contributing to the risk of cadmium-mediated lung toxicity exposed to cigarette smoke