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EUR20.36 EUR65.36

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Description

doi: 10.1016/j.cmet.2016.10.011

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Methylated CpG islands are typically associated with heterochromatin, partly due to the recruitment of methyl-CpG binding proteins, which in turn recruit histone deacetylases and other chromatin-remodeling complexes to promote transcriptional repression ( In addition, histone methylation represents another major epigenetic mechanism that regulates chromatin structure and gene expression

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Subsequent studies led to the establishment of a mouse embryonal carcinoma cell line, enabling detailed analysis of its molecular characteristics

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