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Women who push through unbearable side effects at a new dose tier often develop a negative psychological association with injections that undermines long-term adherence

Li T, Tu L, Gu R, Yang XL, Liu XJ, Zhang GP, et al

Body fat percentage Same BMI, 2x body fat

When starting GLP-1 medications, doctors usually begin with a low dose and increase it slowly over several weeks or months to reduce side effects, especially nausea and stomach upset

Many people start treatment because they want the scale to move, but the most important part of medical weight loss often begins after the first major results appear

As a result, studies suggest calorie intake may drop by up to 39%