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The unfolded protein response within ER activate the PERK-NRF2 axis, inducing antioxidant gene expression to alleviate oxidative stress [143]

240242 Induction of AKI in animals by ischemia, radiocontrast agents, cisplatin, or rhabdomyolysis all induce oxygen tensions below 10 mm Hg deep within kidney tissue

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Aside from diminishing sleep quality, alcohol can also result in the dreaded hangxiety effect, whereby one feels a mix of low mood, restlessness, nervousness, and anxiety the day after drinking

Oxidative stress and psychological disorders