Vitamin B12 Deficiency Long-term use of metformin can interfere with vitamin B12 absorption in the stomach and small intestine, leading to a deficiency in about 6% to 30% of users - especially those on higher doses or taking it for four years or longer
Oncotarget 7 , 5019550214 (2016)
To reduce gastrointestinal symptoms, eat smaller, more frequent meals rather than large portions, avoid high-fat and spicy foods that may worsen nausea, and stay well-hydrated throughout the day
Preliminary data published in June 2023 also suggests that GLP-1 drugs 'could modulate crucial pathways in the pathogenesis of inflammatory bowel disease (IBD), such as chronic inflammation circuits, intestinal tight junctions, and gut microbiome dysbiosis, setting the stage for human trials to investigate the role of these agents in the treatment of IBD among people with or without diabetes and obesity' (Arvanitakis, Theocharis, Popovic
Not everyone needs the maximal efficacy of a triple agonist
By choosing clean, simple ingredients, youre not just avoiding "smelly" side effectsyoure investing in your long-term health and honoring a legacy of excellence
