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the SURMOUNT-1 trial reported up to 22% with tirzepatide over 72 weeks

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These companies are expected to maintain ~85% market share in mid- to long-term

Green Tea Extract at the levels used in supplements has a generally favorable safety profile in healthy adults, though high-dose Green Tea Extract has been associated with rare cases of liver stress in susceptible individuals -- a concern at doses significantly higher than what is typically found in supplement formulations