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Vitamin B 12 deficiency symptoms may include: strange sensations, numbness, or tingling in the hands, legs, or feet difficulty walking (staggering, balance problems) anemia a swollen, inflamed tongue difficulty thinking and reasoning (cognitive difficulties), or memory loss weakness fatigue While an experienced physician may notice the symptoms and be able to detect a vitamin B 12 deficiency with a good interview and physical exam, a blood test is needed to confirm the condition

When comorbid intellectual disability and/or birth defects are present, those with autism spectrum disorders are more likely than those without autism spectrum disorders to have cancer in their early years

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Enhanced cardiac akt/protein kinase B signaling contributes to pathological cardiac hypertrophy in part by impairing mitochondrial function via transcriptional repression of mitochondrion-targeted nuclear genes