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Indeed 5-HT 2C agonists appear to regulate DA neurotransmission by decreasing DA cell activity in the VTA, a region also rich in GHSR1a expression (Di Giovanni et al., 2000)

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Based on the phosphoproteomic profiling we then inferred the upstream kinases responsible for the differential phosphorylation observed in each treatment versus control, using a kinase enrichment analysis ( Figure 6 )

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